main webpage
W Topic
Epilepsy
Nature Neuroscience • Vol 28 • No 4
Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks
2025
Abstract The temporal order of a sequence of events has been thought to be reflected in the ordered firing of neurons at different phases of theta oscillations. Here we assess this by measuring single neuron activity (1,420 neurons) and local field potentials…
Article

Epilepsy

Group of neurological disorders causing seizures

Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. An epileptic seizure is the clinical manifestation of an abnormal, excessive, purposeless and synchronized electrical discharge in the brain cells called neurons. The occurrence of two or more unprovoked seizures defines epilepsy. The occurrence of just one seizure may warrant the definition (set out by the International League Against Epilepsy) in a more clinical usage where recurrence may be able to be prejudged. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical activity in the brain.

Exploring foci of:
Nature Neuroscience • Vol 28 • No 4
Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks
2025
Abstract The temporal order of a sequence of events has been thought to be reflected in the ordered firing of neurons at different phases of theta oscillations. Here we assess this by measuring single neuron activity (1,420 neurons) and local field potentials (921 channels) in the medial temporal lobe of 16 patients with epilepsy performing a working-memory task for temporal order. During memory maintenance, we observe theta oscillations, preferential firing of single neurons to theta phase and a close relationshi…
Click Epilepsy Vs:
Neuroscience
Neuron
Computer Science
Artificial Intelligence
Biology
Cognition