APPRAISE: A Tool for Appraising Potential for Bias in Real-World Evidence Studies on Medication Effectiveness or Safety Article Swipe

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real world evidence real world data risk analysis (engineering) data science business computer science medicine internal medicine

Katsiaryna Bykov , A. Jaksa , Jennifer L. Lund , Jessica M. Franklin , Cynthia J. Girman , Madlen Gazarian , Hongbo Yuan , Stephen Duffield , Seamus Kent , Elisabetta Patorno ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1016/j.jval.2025.07.024 · OA: W4413001560

APPRAISE is a tool to guide bias assessment in observational studies on medication comparative effectiveness or safety. Although the tool was designed for HTA, it will be useful for many other users of RWE and will help guide optimized RWE generation.