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bioRxiv (Cold Spring Harbor Laboratory)
Prediction of SARS-CoV-2 transmission dynamics based on population-level cycle threshold values: A Machine Learning and mechanistic modeling study
2023
Abstract Background Polymerase chain reaction (PCR) cycle threshold (Ct) values can be used to estimate the viral burden of Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2) and predict population-level epidemic trends. We investigated the use…
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Geometry

Branch of mathematics

Geometry (from Ancient Greek __ γεωμετρία (_geōmetría) 'land measurement'; from __ γῆ () 'earth, land' and __ μέτρον (métron) 'a measure') is a branch of mathematics concerned with properties of space such as the distance, shape, size, and relative position of figures. Geometry is, along with arithmetic, one of the oldest branches of mathematics. A mathematician who works in the field of geometry is called a _geometer. Until the 19th century, geometry was almost exclusively devoted to Euclidean geometry, which includes the notions of point, line, plane, distance, angle, surface, and curve, as fundamental concepts.

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bioRxiv (Cold Spring Harbor Laboratory)
Prediction of SARS-CoV-2 transmission dynamics based on population-level cycle threshold values: A Machine Learning and mechanistic modeling study
2023
Abstract Background Polymerase chain reaction (PCR) cycle threshold (Ct) values can be used to estimate the viral burden of Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2) and predict population-level epidemic trends. We investigated the use of machine learning (ML) and epidemic transmission modeling based on Ct value distribution for SARS-CoV-2 incidence prediction during an Omicron-predominant period. Methods Using simulated data, we developed a ML model to predict the reproductive number based…
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