A multicentre observational study to investigate feasibility of a direct oral penicillin challenge in de-labelling ‘low risk’ patients with penicillin allergy by non-allergy healthcare professionals (SPACE study): Implications for healthcare systems Article Swipe

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Mamidipudi Thirumala Krishna , Rashmeet Bhogal , Bee Yean Ng , Kornelija Kildonaviciute , Yogini Jani , Iestyn Williams , Jonathan Sandoe , Rachel Pollard , Nicola Jones , Louise Dunsmure , Neil Powell , Chidanand Hullur , Ariyur Balaji , Catherine Moriarty , Beverley Jackson , Amena Warner , Ron Daniels , Robert West , Caroline Thomas , Siraj Misbah , Louise Savic ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.1016/j.jinf.2024.01.015

DPCs can be delivered by non-allergy HCPs. A high proportion of patients with PALs did not progress in the study pathway. Strategies to deliver DPC at optimal points of the care pathway are needed to enhance uptake. Elective settings offer greater opportunities than acute settings for DPC. The safety and simplicity of DPCs lends itself to adoption by healthcare systems beyond the UK, including in resource-limited settings.

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Medicine Observational study Allergy Penicillin Informed consent Internal medicine Odds ratio Health care Intensive care medicine Pediatrics Antibiotics Immunology Alternative medicine Pathology Biology Economics Microbiology Economic growth

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Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.jinf.2024.01.015
PDF: http://www.journalofinfection.com/article/S0163445324000343/pdf
OA Status: gold
Cited By: 16
References: 30
Related Works: 10
OpenAlex ID: https://openalex.org/W4391578234

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