Improving on polygenic scores across complex traits using select and shrink with summary statistics (S4) and LDpred2 Article Swipe
Jonathan P. Tyrer
,
Pei-Chen Peng
,
Amber A DeVries
,
Simon A Gayther
,
Michelle R. Jones
,
Paul D.P. Pharoah
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1186/s12864-024-10706-3
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1186/s12864-024-10706-3
Taken together, the S4 + LDpred2 method represents an improvement in overall PGS accuracy across multiple phenotypes and populations.
Related Topics To Compare & Contrast
Concepts
Biology
Statistics
Summary statistics
Computational biology
Evolutionary biology
Genetics
Mathematics
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s12864-024-10706-3
- OA Status
- gold
- Cited By
- 3
- References
- 35
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4402596262
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