main webpage W Topic Neuroscience Proceedings for Annual Meeting of The Japanese Pharmacological Society • Vol 92 • No 0 Analyzing task-related neural activity with two-photon calcium imaging from behaving mice 2019 Animals process and integrate sensory inputs to generate appropriate behavioral output. However, neural mechanisms underlying this process remain unclear. Here we established a short-term, visual discrimination task for head-fixed mice combined with in vivo t… Article Open Neuroscience Open Article Page

Neuroscience

Scientific study of the nervous system Neuroscience is the scientific study of the nervous system (including both the central nervous system and the peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences. Critical Symbolic Virtual Narrative Open Neuroscience Open Article Page

Exploring foci of: Proceedings for Annual Meeting of The Japanese Pharmacological Society • Vol 92 • No 0 Analyzing task-related neural activity with two-photon calcium imaging from behaving mice 2019 Animals process and integrate sensory inputs to generate appropriate behavioral output. However, neural mechanisms underlying this process remain unclear. Here we established a short-term, visual discrimination task for head-fixed mice combined with in vivo two-photon imaging to relate neural activity to behavior. Viral vectors encoding the calcium indicator protein GCaMP6m were injected into the visual cortex of adult C57BL/6j mice. Water-restricted mice were trained to discriminate a target stimulus consisting o… Open Article Page

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Explore Neuroscience W Topic Neuroscience Proceedings for Annual Meeting of The Japanese Pharmacological Society • Vol 92 • No 0 Analyzing task-related neural activity with two-photon calcium imaging from behaving mice 2019 Animals process and integrate sensory inputs to generate appropriate behavioral output. However, neural mechanisms underlying this process remain unclear. Here we established a short-term, visual discrimination task for head-fixed mice combined with in vivo t… Article Critical Symbolic Virtual Narrative Open Neuroscience Open Article Page