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Regression Toward The Mean
Chemistry - A European Journal • Vol 31 • No 38
Convergent Approach Toward ADP‐Ribosylated Peptides via a Chemoselective Phosphate Condensation
2025
Abstract The preparation of well‐defined ADP‐ribosylated peptides is essential for studying the functional implications of this post‐translational modification. While methodologies exist for the chemical synthesis of short oligo‐ADPr fragments and mono‐ADP‐ri…
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Regression Toward The Mean

Statistical phenomenon

In statistics, regression toward the mean (also called reversion to the mean , and reversion to mediocrity ) is the phenomenon where if one sample of a random variable is extreme, the next sampling of the same random variable is likely to be closer to its mean. Furthermore, when many random variables are sampled and the most extreme results are intentionally picked out, it refers to the fact that (in many cases) a second sampling of these picked-out variables will result in "less extreme" results, closer to the initial mean of all of the variables.

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Chemistry - A European Journal • Vol 31 • No 38
Convergent Approach Toward ADP‐Ribosylated Peptides via a Chemoselective Phosphate Condensation
2025
Abstract The preparation of well‐defined ADP‐ribosylated peptides is essential for studying the functional implications of this post‐translational modification. While methodologies exist for the chemical synthesis of short oligo‐ADPr fragments and mono‐ADP‐ribosylated peptides separately, combining the two distinct chemistries, required to assemble them, has remained challenging. In this research, we employ a methodology for the regio‐ and chemoselective condensation of two phosphomonoesters to convergently instal…
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Missile Approach Warning System
Reggio Emilia Approach
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