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Summary Statistics
BMC Genomics • Vol 25 • No 1
Improving on polygenic scores across complex traits using select and shrink with summary statistics (S4) and LDpred2
2024
Taken together, the S4 + LDpred2 method represents an improvement in overall PGS accuracy across multiple phenotypes and populations.
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Summary Statistics

Type of statistics

In descriptive statistics, summary statistics are used to summarize a set of observations, in order to communicate the largest amount of information as simply as possible. Statisticians commonly try to describe the observations in

  • a measure of location, or central tendency, such as the arithmetic mean
  • a measure of statistical dispersion like the standard mean absolute deviation
  • a measure of the shape of the distribution like skewness or kurtosis
  • if more than one variable is measured, a measure of statistical dependence such as a correlation coefficient

A common collection of order statistics used as summary statistics are the five-number summary, sometimes extended to a seven-number summary, and the associated box pl…

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BMC Genomics • Vol 25 • No 1
Improving on polygenic scores across complex traits using select and shrink with summary statistics (S4) and LDpred2
2024
Taken together, the S4 + LDpred2 method represents an improvement in overall PGS accuracy across multiple phenotypes and populations.
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