Clinical Validation of MyProstateScore 2.0 Testing Using First-Catch, Non–Digital Rectal Examination Urine

Jeffrey J. Tosoian , Yuping Zhang , Jacob I. Meyers , Spencer Heaton , Javed Siddiqui , Lanbo Xiao , Keavash Assani , Daniel A. Barocas , Ashley E. Ross , Zoey Chopra , Grace Herron , Jerome Edelson , Nathan J. Graham , Udit Singhal , Simpa S. Salami , Todd M. Morgan , Ganesh S. Palapattu , John Wei , Arul M. Chinnaiyan ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1097/ju.0000000000004421

Using first-catch urine, MPS2 meaningfully improved the proportion of biopsies avoided relative to PCPTrc while maintaining highly sensitive detection of GG ≥ 2 cancer. Non-DRE testing provides a convenient, objective, and highly accurate testing option to reduce the need for imaging and biopsy in men with elevated PSA.

Concepts

Medicine Rectal examination Urine Urology Gynecology Internal medicine Prostate Cancer

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Type: article
Language: en
Landing Page: https://doi.org/10.1097/ju.0000000000004421
OA Status: hybrid
Cited By: 3
Related Works: 10
OpenAlex ID: https://openalex.org/W4406735428

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